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李淑艳生化 ,副教授

 电话:82801622

 E-mail:shuyanli@bjmu.edu.cn

 办公地址:

主要学习及工作经历

1990.9-1995.7 北京医科大学护理专业 本科阶段 

1995.7-1998.7 北京友谊医院 

 1998.8-2003.7 北京大学医学部细胞生物学系硕士阶段

于2000年转入生物化学与分子生物学系 博士阶段

2003.8至今 北京大学医学部生化与分子生物学系 工作
获奖情况

2010年度医学部优秀青年学者 

2010年度医学部基础医学院优秀SCI论文二等奖 

010及2009年医学部专业技术岗位青年人才支持计划 2003年度“北京大学医学部优秀SCI论文”三等奖

研究方向 肿瘤表观调控与肿瘤发生机制研究
基金来源 国家自然科学基金、北京市自然科学基金
代表论文

1. Shu-Yan Li(李淑艳)*#, Yu-Hong Jia, Wen-Ge Sun, Yuan Tang, Guo-Shun An, Ju-Hua Ni, Hong-Ti Jia. Stabilization of Mitochondrial Function by Tetramethylpyrazine Protects against Kainate-Induced Oxidative Lesions in the Rat Hippocampus. Free Rad Biol Med 2010, 48:597-608 (IF 6.081) 

2. Shu-Yan Li (李淑艳) *#, Wen-Ge Sun, Yu-Hong Jia, Guo-Sheng Wu, Guo-Shun An, Ju-Hua Ni, Hong-Ti Jia. Calcium Signal-Initiated Early Activation of NF-κB in Neurons Is a Neuroprotective Event in Response to Kainic Acid-Induced Excitoxicity. Biochemistry(moscow)/Biokhimika 2010,75:101-109 ( IF 1.327) 

3. Hai-Jun Zhang*, Wen-Juan Li, Yan-Yan Gu, Shu-Yan Li, Guo-Shun An, Ju-Hua Ni, Hong-Ti Jia#. p14ARF interacts with E2F factors to form p14ARF-E2F/partner-DNA complexes repressing E2F-dependent transcription. J Cell Biochem 2010, 109:693-701. 

4. Hai-Jun Zhang*, Wen-Juan Li, Sheng-Yong Yang, Shu-Yan Li, Ju-Hua Ni, Hong-Ti Jia#. 8-Chloro-adenosine-induced E2F1 promotes p14ARF gene activation in H1299 cells through displacing Sp1 from multiple overlapping E2F1/Sp1 sites. J Cell Biochem 2009, 106:464-472. 

 5. Yu-Hong Jia*,Xuan Zhu,Shu-Yan Li,Ju-Hua Ni,Hong-Ti Jia#. Kainate exposure suppresses activation of GluR2 subunit promoter in primary cultured cerebral cortical neurons through induction of RE1-silencing transcription factor. Neurosci Lett 2006, 403:103-108. 

6. 李淑艳*、李增刚、李隽、倪菊华、贾弘禔#. 听原性惊厥易感大鼠下丘GluR2的表达及Q/R位点编辑水平。中国生物化学与分子生物学报 2005, 21:78-826. 

 7. Shu-Yan Li*(李淑艳), Ju-Hua Ni, De-Sheng Xu, Hong-Ti Jia#. Down-regulation of GluR2 is associated with Ca2+-dependent protease activities in kainate-induced apoptotic cell death in cultured rat hippocampal neurons. Neurosci Lett 2003, 352: 105-108(IF: 2.1) 

8. Shu-Yan Li*(李淑艳), De-Sheng Xu, Hong-Ti Jia#. AGS-induced expression of Narp is concomitant with expression of AMPA receptor subunits GluR1 and GluR2 in hippocampus but not inferior colliculus of P77PMC rats. Neurobiol Dis 2003, 14: 328-335(IF 5.153)

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