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康继宏生理 ,教授,博导

 电话:82805613

 E-mail:kangjihong@bjmu.edu.cn

 办公地址:学院路38号北京大学医学部生理楼328

主要学习及工作经历

1989.9-1993.7 中国药科大学药物分析专业 本科生 

1995.9-1999.7 中国药科大学药物分析专业 硕士生 

2000.5- 2005.6 加拿大拉瓦尔大学(Laval University)生理与内分泌专业博士生 

2005.7- 2008.12 加拿大拉瓦尔大学(Laval University)分子内分泌实验室博士后

1993.8-1999.11 中国药科大学分析化学教研室助教 

2009.4- 2010.7 北京大学医学部生理学与病理生理学系 讲师 

2010.8-2021.7  北京大学医学部生理学与病理生理学系 副教授

2021.8-至今     北京大学医学部生理学与病理生理学系 教授

研究方向 多囊卵巢综合征的病理机制研究
基金来源 国家自然科学基金面上项目
代表论文

1.  Shihe Liu#, Qiyang Yao#, Xiaolian Li, Haowen Wu, Changwei Sun, Wenpei Bai*, Jihong Kang*. Effects of a ketogenic diet on reproductive and metabolic phenotypes in mice with polycystic ovary syndrome. Biology of Reproduction, 2023, 108(4): 597-610.

2.  Qiyang Yao, Xin Zou, Shihe Liu, Haowen Wu, Qiyang Shen and Jihong Kang*. Oxidative Stress as a Contributor to Insulin Resistance in the Skeletal Muscles of Mice with Polycystic Ovary Syndrome. International Journal of Molecular Sciences, 2022, 23(19): 11384.

3.  Menliang Zhu, Qiyang Shen, Xiaolian Li, Jihong Kang*. Removal of peri-ovarian adipose tissue affects follicular development and lipid metabolism. Biology of Reproduction, 2020, 103(6): 1199-1208

4.  Shen Q#, Bi H#, Yu F, Fan L, Zhu M, Jia X, Kang J*. Non-targeted Metabolomic Analysis of Skeletal Muscle in a Dehydroepiandrosterone-Induced Mouse Model of Polycystic Ovary Syndrome. Mol Reprod Dev. 2019, 86(4): 370-378

5.  Xi Song#, Qiyang Shen#, Liting Fan, Qiuxiao Yu, Xiao Jia, Yu Sun, Wenpei Bai, and Jihong Kang*. Dehydroepiandrosterone-induced activation of mTORC1 and inhibition of autophagy contribute to skeletal muscle insulin resistance in a mouse model of Polycystic Ovary Syndrome. Oncotarget, 2018, 9(15): 11905-11921

6.  Yu Q#, Hao S#, Wang H, Song X, Shen Q, Kang J*. Depression-Like Behavior in a Dehydroepiandrosterone-Induced Mouse Model of Polycystic Ovary Syndrome. Biology of Reproduction, 2016; 95(4): 79; 1-10 (#, co-first author; *, corresponding author) (recommended by Faculty of 1000), Rankings: Very Good)

7.  Min Gao#, Rong Cao#, Shengnan Du#, Xiao Jia, Senfeng Zheng, Shizheng Huang, Qifei Han, Jia Liu, Xiaoyan Zhang, Yifei Miao, Jihong Kang*, Jan-Åke Gustafsson*, and Youfei Guan*. Disruption of prostaglandin E2 receptor EP4 impairs urinary concentration via decreasing aquaporin 2 in renal collecting ducts. PNAS,  2015, 112(27): 8397-402 (recommended by Faculty of 1000, Rankings: Good) Q1

8.  Hao Lai#, Xiao Jia#, Qiuxiao Yu, Chenglu Zhang, Jie Qiao, Youfei Guan, and Jihong Kang*. High-Fat Diet Induces Significant Metabolic Disorders in a Mouse Model of Polycystic Ovary Syndrome. Biology of Reproduction, 2014, 91(5):127; 1-11 (recommended by Faculty of 1000, Rankings: Exceptional)

9.   Chen X, Jia X, Qiao J, Guan Y, Jihong Kang*. Adipokines in Reproductive Function - a Link between Obesity and Polycystic Ovary Syndrome. Journal of Molecular Endocrinology, 2013, 50(2): R21-R37

10.  Jihong Kang and Serge Rivest*. Lipid Metabolism and neuroinflammation in Alzheimer’s Disease: a role for Liver X Receptors. Endocrine Reviews, 2012, 33(5): 715-746

11.  Kewei Shang, Xiao Jia, Jie Qiao, Jihong Kang*, Youfei Guan. Endometrial Abnormality in Women with Polycystic Ovary Syndrome. Reproductive Sciences, 2012, 19(7): 674 - 683

12.  Jihong Kang and Serge Rivest*. MyD88-deficient bone marrow Cells accelerate onset and reduce survival in a mouse model of amyotrophic lateral sclerosis. Journal of Cell Biology, 2007, 179(6); 1219-30Highlighted paper

13.  Jihong Kang, Pierre Chapdelaine, Philippe Y. Laberge and Michel A. Fortier*. Functional Characterization of Prostaglandin Transporter During Decidualization of Human Endometrial Stromal Cells. Human Reproduction, 2006, 21(3):592-599

14.  Jihong Kang, Pierre Chapdelaine, Julie Parent, Eric Madore, Philippe Y. Laberge and Michel A. Fortier*. Expression of Human Prostaglandin Transporter in the Human Endometrium across the Menstrual Cycle. Journal of Clinical Endocrinology and Metabolism, 2005, 90(4):2308-2313

15.  Jihong Kang, Ali Akoum, Pierre Chapdelaine, Philippe Laberge, Patrice E. Poubelle and Michel A. Fortier*. Independent regulation of prostaglandins and monocyte chemoattractant protein-1 by interleukin-1b and hCG in human endometrial cells. Human Reproduction, 2004, 19(11):2465-2473

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