主要学习及工作经历 1994.9-1998.7 北京师范大学化学系本科 2000.8-2005.5 美国克利夫兰州立大学博士研究生、教学助理、研究助理 2005.3-2007.10 PrognostiX Inc. 研究科学家 2007.11-- 北京大学病理生理学 副教授

主要学术任职 中国病理生理学会会员； 福建省心血管所专家委员会委员。

获奖情况 美国克利夫兰医院“优秀研究生”奖与“Elsa Albrecht Fellowship”奖； 美国克利夫兰州立大学区域论坛“Lubrizol”奖； 中国病理生理学会青年优秀论文一等奖； 美国专利Risk markers for cardiovascular disease（美国专利申请号20050239136）。

研究方向 心血管氧化与蛋白质组学、脂质组学、代谢组学。

基金来源 国家自然基金委青年面上基金；北京市面上基金；教育部“新世纪优秀人才支持计划”基金；科技部“973”重大基础研究骨干基金；教育部博士点基金与回国留学人员启动基金。

代表论文 1. Zhang T, Yao S, Wang P, Yin C, Xiao C, Qian M, Liu D, Zheng L, Meng W, Zhu H, Liu J, Xu H, Mo X. APOA-II DIRECTS MORPHOGENETIC MOVEMENTS OF ZEBRAFISH EMBRYO BY PREVENTING CHROMOSOME FUSION DURING NUCLEAR DIVISION IN YOLK SYNCYTIAL LAYER. the Journal of Biological Chemistry. 2011 Jan 6. [Epub ahead of print] 2. Peng DQ, Brubaker G, Wu Z, Zheng Lemin, Willard B, Kinter M, Hazen SL, Smith JD. “Apolipoprotein A-I Tryptophan Substitution Leads to Resistance to Myeloperoxidase-Mediated Loss of Function” Arterioscler Thromb Vasc Biol. (2008) 28(11) , 2063-70. 3. Wu Z, Wagner M, Zheng Lemin, Parks J, Shy J, Smith J, Gogonea V, Hazen S. “The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction” Nature Structural & Molecular Biology. (2007) 14（9）861-8. 4. Ghosh S, Janocha AJ, Aronica MA, Swaidani S, Comhair SA, Xu W, Zheng Lemin, Kaveti S, Kinter M, Hazen SL, Erzurum SC. “Nitrotyrosine proteome survey in asthma identifies oxidative mechanism of catalase inactivation” the Journal of Immunology. (2006) 176(9), 5587-97. 5. Comhair S, Xu W, Ghosh S, Thunnissen F, Almasan A, Calhoun W, Janocha A, Zheng Lemin, Hazen S, Erzurum S. “Superoxide dismutase inactivation in pathophysiology of asthmatic airway remodeling and reactivity” the American Journal of Pathology. (2005) 166, 663-674. 6. Zheng Lemin, Settle M, Brubaker G, Schmitt D, Hazen S, Smith J, Kinter M. “Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages” the Journal of Biological Chemistry. (2005) 280, 38-47. 7. Peng D, Wu Z, Brubaker G, Zheng Lemin, Settle M, Gross E, Kinter M, Hazen S, Smith J. “Tyrosine modification is not required for myeloperoxidase-induced loss of apolipoprotein A-I functional activities” the Journal of Biological Chemistry. (2005) 280(40), 33775-84. 8. Nicholls S, Zheng Lemin, Hazen S. “Formation of dysfunctional high-density lipoprotein by myeloperoxidase” Trends in Cardiovascular Medicine. (2005) 15(6), 212-9. 9. Zheng Lemin, Nukuna B, Brennan M, Sun M, Goormastic M, Settle M, Schmitt D, Fu X, Thomson L, Fox P, Ischiropoulos H, Smith J, Kinter M, and Hazen S. “Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease” the Journal of Clinical Investigation. (2004) 114, 529-541. 10. Samoszu M, Brennan ML, To V, Leonor L, Zheng Lemin, Fu X, Hazen SL. “Association between nitrotyrosine levels and microvascular density in human breast cancer” Breast Cancer Research and Treatment. (2002) 74, 271-278.