主要学习及工作经历 1998.9-2002.7 天津科技大学生物化学本科 2002.9-2008.1 复旦大学博士 2008.2-2009.6 耶鲁大学博士后 2009.7-2013.2 安德森肿瘤中心博士后 基金来源： 2013.2-2014.8 安德森肿瘤中心讲师

主要学术任职 International Journal of Clinical and Experimental Medicine 杂志编委会委员 美国癌症协会 (AACR)会员 美国生化和分子生物学 (ASBMB)会员 美国遗传学会 (GSA) 会员 Nucleic Acid Research, Cell Cycle, FEBS Journal, PLoS one, Molecular Oncology, Cancer Letters, Journal of Cellular Biochemistry, Journal of Cellular and Molecular Medicine 等国际期刊审稿人

获奖情况 The 4th International Symposium on DNA Damage Response & Human Disease (2013) 最佳论文  一等  

研究方向 放射肿瘤生物学，DNA损伤修复与家族性乳腺癌

基金来源 北大百人 100万元 自然科学基金面上项目 75万元

代表论文 1.Wang J, Gong Z, Chen J. TopBP1 Controls BLM Protein Level to Suppress Sister Chromatid Exchange. Mol Cell 52 (5), 667-678. 2.Wang J, Leung JW, Gong Z, Feng L, Shi X, Chen J. PHF6 regulates cell cycle progression by suppressing ribosomal RNA synthesis. J Biol Chem. 288(5):3174-83 2013 PMID: 23229552 3.Wang J, Gong Z, Chen J. Chen MDC1 collaborates with TopBP1 in DNA replication checkpoint control. J Cell Biol. 193(2):267-73 2011 PMID: 21482717 4.Liu N, Wang J (co-first), Wang J, Wang R, Liu Z, Yu Y, Lu H. ING5 Is a Tip60 Cofactor That Acetylates p53 in Response to DNA Damage. Cancer Res. 73(12):3749-60 2013 PMID: 23576563 5.Feng L, Fong KW, Wang J, Wang W, Chen J. RIF1 counteracts BRCA1-mediated end resection during DNA repair. J Biol Chem. 288(16):11135-43. 2013 Mar PMID: 23486525 6.Leung JW, Ghosal G, Wang W, Shen X, Wang J, Li L, Chen J. Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress. J Biol Chem 288(9):6342-50. 2013 PMID: 23329831 7.Feng L, Wang J, Chen J. The Lys63-specific deubiquitinating enzyme BRCC36 is regulated by two scaffold proteins localizing in different subcellular compartments. J Biol Chem. 285(40):30982-8 2010 PMID: 20656690 8.Wang J, Chen J.SIRT1 regulates autoacetylation and histone acetyltransferase activity of TIP60 J Biol Chem. 285(15):11458-64. 04/2010. PMCID: PMC2857024 9.Wang J, Liu N, Liu Z, Li Y, Song C, Yuan H, Li YY, Zhao X, Lu H. The orphan nuclear receptor Rev-erbβ recruits Tip60 and HDAC1 to regulate Apolipoprotein CIII Promoter. Biochim Biophys Acta. 1783(2):224-36. 2008 PMID:17996965 10.Wang J, Li Y, Zhang M, Liu Z, Wu C, Yuan H, Li Y, Zhao X, Lu H. A zinc finger HIT domain-containing protein, ZNHIT-1, interacts with orphan nuclear hormone receptor Rev-erbβ and removes Rev-erbβ-induced inhibition of apoCIII transcription. FEBS J. 274(20):5370-81. 2007 PMID: 17892483