2008.9-2013.7 北京大学基础医学专业本科生
2013.8-2016.7 北京大学病理学专业博士研究生
2016.08-2021.07 北京大学基础医学院生物化学与生物物理学系 讲师
2021.08-至今 北京大学基础医学院生物化学与生物物理学系 副研究员、博士生导师
国家自然科学基金面上项目, 32171224, DNA损伤修复关键复合物shieldin的结构和功能研究, 2022-01-01 至 2025-12-31, 58万元
国家自然科学基金青年科学基金项目,31800626,OTU家族去泛素化酶的结构和功能研究,2019/01-2021/12,24万元
(1) Ling Liang#*; Jiawen Feng#; Peng Zuo; Juan Yang; Yishuo Lu; Yuxin Yin*; Molecular basis for assembly of the shieldin complex and its implications for NHEJ, Nature Communications, 2020, 11: 1972
(2) Yuan Wang#; Chunlei Zhang#; Wenzhong Yang; ShiPeng Shao; Xinmin Xu; Yujie Sun; Pilong Li; Ling Liang*; Congying Wu*; LIMD1 phase separation contributes to cellular mechanics and durotaxis by regulating focal adhesion dynamics in response to force, Developmental Cell, 2021, 56(9): 1-13
(3) Zonglin Dai#; Ling Liang#; Weize Wang#; Peng Zuo; Shang Yu; Yaqi Liu; Xuyang Zhao; Yishuo Lu; Yan Jin; Fangting Zhang; Dian Ding; Weiwei Deng; Yuxin Yin, Structural insights into the ubiquitylation strategy of the oligomeric CRL2FEM1B E3 ubiquitin ligase, EMBO Journal, 2024, 43(6): 1089-1109
(4) Weize Wang#, Ling Liang#*, Zonglin Dai#, Peng Zuo, Shang Yu, Yishuo Lu, Dian Ding, Hongyi Chen, Hui Shan, Yan Jin, Youdong Mao, Yuxin Yin*, A conserved N-terminal motif of CUL3 contributes to assembly and E3 ligase activity of CRL3KLHL22, Nature Communications, 2024, 15: 3789
(5) Chuanda Zhu, ZongLin Dai, Lu Qin, Jing Wang, Ling Liang*. Efficient cytosolic delivery of proteins enabled by modular fusion protein. Chemical Engineering Journal, 2024; 497(1):154619
(6) Chuanda Zhu#; Xi Chen#; Jingjing Gong; Jiao Liu; Lidong Gong; Zeliang Yang; Zhenyu Zhu; Qiang Zhang; Tiancheng Li*; Ling Liang*; Zhiqiang Lin*; An elastase nanocomplex with metal cofactors for enhancement of target protein cleavage activity and synergistic antitumor effect, Chemical Engineering Journal, 2024, 485: 149902
友情链接:
北大医学部