2003年-2007年：四川大学生命科学学院生物学基地班，获得学位：学士 

2007年-2013年：北京大学生命科学学院细胞生物学专业，获得学位：博士 

2014年-2019年：北京大学干细胞生物学方向，博士后，获北大清华生命科学联合中心优秀博士后基金资助 

2019年-至今：北京大学干细胞研究中心，副主任，研究员，助理教授

The Innovation, Exploration, Life Medicine青年编委

全能干细胞研究及应用

国家自然科学基金，国家重点研发计划，北京市自然科学基金

1. Xu Y, Zhao J, Ren Y, Wang X, Lyu Y, Xie B, Sun Y, Yuan X, Liu H, Yang W, Fu Y, Yu Y, Liu Y, Mu R, Li C, Xu J, Deng H. Derivation of totipotent-like stem cells with blastocyst-like structure forming potential. Cell Res. 2022 May 4.

2. Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, Xu Y, Dong J, Wang C, Lai W, Zhu J, Xiong L, Zhu D, Li X, Yang W, Yamauchi T, Sugawara A, Li Z, Sun F, Li X, Li C, He A, Du Y, Wang T, Zhao C, Li H, Chi X, Zhang H, Liu Y, Li C, Duo S, Yin M, Shen H, Belmonte JCI, Deng H. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169(2):243-257.

3. Chen S, He YY, Lv LJ, Liu B, Li C, Deng HK, Xu J. Transient Chemical-Mediated Epigenetic Modulation Confers Unrestricted Lineage Potential on Human Primed Pluripotent Stem Cells. Science China Life Sciences. doi/10.1007/s11427-024-2660-3.

4. Li J, Lin X, Xie LF, Zhao J, Han C; Deng H, Xu J. A CRISPR/Cas9-based kinome screen identifies ErbB signaling as a new regulator of human naïve pluripotency and totipotency. Life Medicine. 2023;2(4). lnad037.

5. Liu B, Chen S, Xu Y, Lyu Y, Wang J, Du Y, Sun Y, Liu H, Zhou H, Lai W, Xue A, Yin M, Li C, Bai Y, Xu J, Deng H. Chemically defined and xeno-free culture condition for human extended pluripotent stem cells. Nat Commun. 2021 May 21;12(1):3017.

6. Qu M, Xiong L, Lyu Y, Zhang X, Shen J, Guan J, Chai P, Lin Z, Nie B, Li C, Xu J, Deng H. Establishment of intestinal organoid cultures modeling injury-associated epithelial regeneration. Cell Res. 2021 Mar;31(3):259-271.

7. Wang Q, Sun D, Liang Z, Wang J, Zhong X, Lyu Y, Cao J, Lin Z, Du Y, Miao Z, Lu S, Li C, Xu J, Shi Y, Deng H. Generation of human hepatocytes from extended pluripotent stem cells. Cell Res. 2020;30(9):810-813.

8. Xu J, Du Y, Deng H. Direct lineage reprogramming: strategies, mechanisms, and applications. Cell Stem Cell. 2015;16(2):119-34.

9. Fang R, Liu K, Zhao Y, Li H, Zhu D, Du Y, Xiang C, Li X, Liu H, Miao Z, Zhang X, Shi Y, Yang W, Xu J, Deng H. Generation of naive induced pluripotent stem cells from rhesus monkey fibroblasts. Cell Stem Cell. 2014;15(4):488-497.

10. Sun X, Xu J, Lu H, Liu W, Miao Z, Sui X, Liu H, Su L, Du W, He Q, Chen F, Shi Y, Deng H. Directed Differentiation of Human Embryonic Stem Cells into Thymic Epithelial Progenitor-like Cells Reconstitutes the Thymic Microenvironment In Vivo. Cell Stem Cell. 2013;13(2):230-6.