2006.9 – 2010.7 四川大学基础数学专业 – 理学学士
2010.9 – 2015.7 中国科学院数学与系统科学研究院 – 理学博士
2015.8 – 2018.7 美国圣裘德儿童研究医院 – 博士后
2018.7 – 2021.4 美国密歇根大学 – 博士后
2021.6 至今 北京大学基础医学院医学遗传学系 – 助理教授• 引进人才计划与启动,150万,2021-07-01到2023-12-31
• 优秀青年科学基金项目(海外),国家自然科学基金,针对生物医学大数据的建模与分析,2022年1月1日 - 2024年12月31日,300万,主持
• 面上项目,国家自然科学基金,基于鞍点近似方法的全基因组关联分析研究,2023年1月1日 - 2026年12月31日,54万,主持
• 中韩国际合作项目,国家自然科学基金,全基因组关联分析算法及其在东亚人群中的应用,2024年7月1日 - 2026年12月31日,15万,主持
• 科技部重点专项“生物与信息融合(BT与IT融合)”,中华人民共和国科学技术部,2021YFF1201201,研究生物医学“类脑”智能工作流计算环境,2022年1月1日 - 2024年12月31日,33万元,参与
[1] (代表性论著[1]) Wei Zhou#* Wenjian Bi#*, Zhangchen Zhao#, Kushal K. Dey, Karthik A. Jagadeesh, Konrad J. Karczewski, Mark J. Daly, Benjamin M. Neale, Seunggeun Lee*, Set-based rare variant association tests for biobank scale sequencing data sets. Nature Genetics, 2022, 54(10): 1466-1469.
[2] (代表性论著[2]) Wenjian Bi#, Zhiyu Xu#, Feng Liu, Zhi Xie, Hao Liu, Xiaotian Zhu, Wenge Zhong, Peipei Zhang*, Xing Tang*, Genome-wide analyses reveal the contribution of somatic variants to the immune landscape of multiple cancer type, PLOS Genetics, 2024, 1: e1011134.
[3] (代表性论著[3]) Wenjian Bi#*, Wei Zhou#, Peipei Zhang, Yaoyao Sun, Weihua Yue, Seunggeun Lee*. Scalable mixed model methods for set-based association studies on large-scale categorical data analysis and its application to exome sequencing data in UK Biobank, American Journal of Human Genetics, 2023, 110(5): 762-773.
[4] (代表性论著[4]) Wenjian Bi*, Wei Zhou, Rounak Dey, Bhramar Mukherjee, Joshua N. Sampson, Seunggeun Lee*, Efficient mixed model approach for large-scale genome-wide association studies of ordinal categorical phenotypes. American Journal of Human Genetics, 2021, https://doi.org/10.1016/j.ajhg.2021.03.019.(*共同通讯作者)
[5] (代表性论著[5]) Wenjian Bi, Lars G. Fritsche, Bhramar Mukherjee, Sehee Kim, Seunggeun Lee*, A fast and accurate method for genome-wide time-to-event data analysis and its application to UK-Biobank. American Journal of Human Genetics, 2020, 107(2): 222-233.
[6] (代表性论著[6]) Wenjian Bi, Zhangchen Zhao, Rounak Dey, Lars G Fritsche, Bhramar Mukherjee, Seunggeun Lee*, A fast and accurate method for genome-wide scale phenome-wide G×E analysis and its application to UK Biobank. American Journal of Human Genetics, 2019, 105(6): 1182-1192.
[7] (代表性论著[7]) Wenjian Bi, Yun Li, Matthew P. Smeltzer, Guimin Gao, Shengli Zhao, Guolian Kang*, STEPS: an efficient prospective likelihood approach to genetic association analyses of secondary traits in extreme phenotype sequencing. Biostatistics, 2020, 21(1): 33-49.
[8] (代表性论著[8]) Guolian Kang#*, Wenjian Bi#, Hang Zhang, Stanley Pounds, Cheng Cheng, Sanjay Shete, Fei Zou, Yanlong Zhao, Ji-Feng Zhang, Weihua Yue*, A robust and powerful set-valued approach to rare variant association analyses of secondary traits in case-control sequencing studies. Genetics, 2017, 205(3): 1049-1062.(#共同第一作者)
[9] Hang Zhang#, Wenjian Bi#, Yuehua Cui, Honglei Chen, Jinbo Chen, Yanlong Zhao*, Guolian Kang*, Extreme-value sampling design is cost-benefit only with valid statistical approach for exposure-secondary outcome association analyses. Statistical Methods in Medical Research, 2020, 29 (2): 466-480.(#共同第一作者)
[10] Guolian Kang#*, Wenjian Bi#, Yanlong Zhao*, Ji-Feng Zhang, Jun J. Yang, Heng Xu, Mignon L. Loh, Stephen P. Hunger, Mary V. Relling, Stanley Pounds and Cheng Cheng, A system identification approach to identifying genetic variants in sequencing studies for a binary phenotype, Human Heredity, 2014, 78: 104-116.(#共同第一作者)
[11] Wenjian Bi#, Guolian Kang#*, Yanlong Zhao, Yuehua Cui, Yun Li, Christine M Hartford, Wing Leung and Ji-Feng Zhang*, SVSI: A fast and powerful set-valued system identification approach to identifying rare variants in sequencing studies for ordered categorical traits, Annals of Human Genetics, 2015, 79: 294-309.(#共同第一作者)
[12] Hao Yu#, Wenjian Bi#, Chenxing Liu, Yanlong Zhao, Ji-Feng Zhang, Dai Zhang* and Weihua Yue*, Protein-interaction-network-based analysis for genome-wide association analysis of schizophrenia in Han Chinese population, Journal of Psychiatric Research, 2014, 50: 73-78. (#共同第一作者)
[13] Hao Yu#, Wenjian Bi#, Chenxing Liu, Yanlong Zhao, Dai Zhang and Weihua Yue*, A hypothesis-driven pathway analysis reveals Myelin-related pathways that contribute to the risk of schizophrenia and bipolar disorder, Progress in Neuro-Psychopharmacology & Biological Psychiatry, 2014, 51: 140-145. (#共同第一作者
友情链接:
北大医学部